Early research shows that taking milk thistle extract might reduce liver damage caused by low levels of oxygen in the blood. Tyutyulkova, N., Tuneva, S., Gorantcheva, U., Tanev, G., Zhivkov, V., Chelibonova-Lorer, H., and Bozhkov, S. Hepatoprotective effect of silymarin (carsil) on liver of D- galactosamine treated rats. Basaga, H., Poli, G., Tekkaya, C., and Aras, I. Milk thistle seeds, like all other parts of the plant, can be eaten raw or cooked. Swelling (inflammation) and build up of fat in the liver in people who drink little or no alcohol (nonalcoholic steatohepatitis or NASH). Becker-Schiebe, M., Mengs, U., Schaefer, M., Bulitta, M., and Hoffmann, W. Topical use of a silymarin-based preparation to prevent radiodermatitis : results of a prospective study in breast cancer patients. On the contrary, nyjer is not a thistle at all. Jacobs, B. P., Dennehy, C., Ramirez, G., Sapp, J., and Lawrence, V. A. Effect of addition of silymarin to renin-angiotensin system inhibitors on proteinuria in type 2 diabetic patients with overt nephropathy: a randomized, double-blind, placebo-controlled trial. 2017;15(12):1940-1949. While many things called thistle are edible, I’ll write here about members of the genus Cirsium, the most well-known of which is the bull thistle (C. vulgare). Arzneimittelforschung. View abstract. J.Med.Food 2007;10(3):543-547. Research shows that taking a specific combination product containing milk thistle and other ingredients by mouth for 3 months reduces hot flashes by 73% and night sweats by 69% in people with menopausal symptoms. It' s not clear if these benefits are due to milk thistle or other ingredients. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. View abstract. Effects of silymarin MZ-80 on oxidative stress in patients with alcoholic cirrhosis. View abstract. Biochem Pharmacol 5-28-1992;43(10):2111-2115. View abstract. Theoretically, milk thistle might change the levels of some medications used for lowering cholesterol (statins). Dogs love avocados but they are toxic. Strahlenther.Onkol. Taking milk thistle along with estrogens might decrease the effectiveness of estrogen pills. On the contrary, nyjer is not a thistle at all. Silymarin treatment of obsessive-compulsive spectrum disorders. Randomised double-blinded trial evaluating silymarin for chronic hepatitis C in an Egyptian village: study description and 12-month results. View abstract. Click to see full answer Considering this, how do you know if thistle seed is bad? Sleep quality also improves. Benefit of medicinal liver therapy in general practice. 1988;45(3-4):265-276. 2016;35(5):1091-5. 1976;26(1):69-73. View abstract. Fallah Huseini, H., Larijani, B., Fakhrzadeh, H., Rajabi Pour, B., Akhondzadeh, S., Toliat, T., and Heshmat, R. The clinical trial of Silybum Marianum seed extract (Silymarin) on type II diabetic patients with hyperlipidemia. Biochemical and clinical effects of whey protein supplementation in Parkinson's disease: A pilot study. View abstract. Early research shows that taking a combination supplement containing milk thistle extract improves mental function in people with Alzheimer disease. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others. Taking milk thistle along with some medications that are broken down by the liver can increase the effects and side effects of some medications. J Hepatol. Boerth J, Strong KM. Thistle seed may not have a very long shelf life. Is there anything I can do to help her? Gaedeke, J., Fels, L. M., Bokemeyer, C., Mengs, U., Stolte, H., and Lentzen, H. Cisplatin nephrotoxicity and protection by silibinin. The clinical utility of milk thistle (Silybum marianum) in cirrhosis of the liver. Vostalova J, Vidlar A, Ulrichova J, et al. Locher, R., Suter, P. M., Weyhenmeyer, R., and Vetter, W. Inhibitory action of silibinin on low density lipoprotein oxidation. However, it is slightly bitter due to its silymarin content. View abstract. Lee JI, Narayan M, Barrett JS. Lash DB, Ward S. CYP2C9-mediated warfarin and milk thistle interaction. Lahiri-Chatterjee, M., Katiyar, S. K., Mohan, R. R., and Agarwal, R. A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model. But choosing local, in season, ripe, organic fruits is the best bet. Physiol Res 1998;47(1):1-7. View abstract. View abstract. Mirnezami M, Jafarimanesh H, Rezagholizamenjany M, et al. Sridharan K, Sivaramakrishnan G. Efficacy and safety of iron chelators in thalassemia and sickle cell disease: a multiple treatment comparison network meta-analysis and trial sequential analysis. Dermatol Ther. Doehmer J, Weiss G, McGregor GP, Appel K. Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities. Symptoms of menopause. Summary, Evidence Report/Technology Assessment: Number 21, September 2000. 1996;11(1):55-62. A double-blind controlled randomized clinical trial of phototherapy plus oral Silybum marianum product versus phototherapy alone. View abstract. 1998;20(3):471-479. Dehmlow, C., Murawski, N., and de Groot, H. Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells. View abstract. 2012;55(6):2005-23. Schuppan D, Strosser W, Burkard G, and et al. View abstract. Phytother Res. Fundam.Clin.Pharmacol. Zhang, J. Q., Mao, X. M., and Zhou, Y. P. [Effects of silybin on red blood cell sorbitol and nerve conduction velocity in diabetic patients]. Available at: https://www.ahrq.gov/clinic/epcsums/milktsum.htm. 2015;8:89-96. Milk thistle might decrease how quickly the liver breaks down some medications. Zou, C. G., Agar, N. S., and Jones, G. L. Oxidative insult to human red blood cells induced by free radical initiator AAPH and its inhibition by a commercial antioxidant mixture. View abstract. A double-blind, randomized, placebo-controlled trial on the effects of an herbal preparation in patients with functional dyspepsia [Abstract]. Cavalieri S. A controlled clinical trial of Legalon in 40 patients. View abstract. View abstract. An opossum frequently visiting a bird feeder can be particularly troubling for a bird lover hoping to attract nesting birds to the area, as opossums also eat bird eggs. A type of anxiety marked by recurrent thoughts and repetitive behaviors (obsessive-compulsive disorder or OCD). View abstract. View abstract. Free Radic Biol Med 2012;52(9):1658-65. Milk thistle can also be taken with cholesterol-lowering medications, like statins. View abstract. 2010;16(6):642-645. Moreover, how do you store thistle seeds? Detaille, D., Sanchez, C., Sanz, N., Lopez-Novoa, J. M., Leverve, X., and El Mir, M. Y. Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes. Kidney damage caused by contrast dyes (contrast induced nephropathy). Therapeutic effects of silymarin]. Int J Clin Pharmacol Ther 2002;40(1):2-8. Saller R, Brignoli R, Melzer J, Meier R. An updated systematic review with meta-analysis for the clinical evidence of silymarin. Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP. This survey is being conducted by the WebMD marketing sciences department. A bioavailability cross-over randomised study on silybin. Carini, R., Comoglio, A., Albano, E., and Poli, G. Lipid peroxidation and irreversible damage in the rat hepatocyte model. Protection by the silybin-phospholipid complex IdB 1016. View abstract. Barbosa CC, Nishimura AN, Santos MLD, et al. Zeitschrift fur Allgemeinmedizin 1998;74:577-584. Buzzelli G, Moscarella S, Giusti A, et al. View abstract. 1996;62(5):187-193. 1-11-2009;150(2):73-79. Comoglio, A., Tomasi, A., Malandrino, S., Poli, G., and Albano, E. Scavenging effect of silipide, a new silybin-phospholipid complex, on ethanol-derived free radicals. El-Shitany NA, Hegazy S, El-Desoky K. Evidences for antiosteoporotic and selective estrogen receptor modulator activity of silymarin compared with ethinylestradiol in ovariectomized rats. Deng JW, Shon JH, Shin HJ, et al. View abstract. Carcinogenesis 2001;22:1399-403. Aller R, Izaola O, Gómez S, et al. 2015;19(16):3118-24. Mol.Pharm. There is evidence that milk thistle extract improves markers of liver injury in people with NAFLD. Medicine (Baltimore) 2018;97(37):e12243. View abstract. Current Therapeutic Research 1994;55(5):537-545. Acta Med Hung. J Ethnopharmacol 2011;137(3):1328-1333. Nurse Drug Alert 1999;23(7):51. Silymarin in non-cirrhotics with non-alcoholic steatohepatitis: A randomized, double-blind, placebo controlled trial. 2017;96(49):e9061. Sonnenbichler, J. and Zetl, I. Biochemical effects of the flavonolignane silibinin on RNA, protein and DNA synthesis in rat livers. Feher, J., Lang, I., Nekam, K., Muzes, G., and Deak, G. Effect of free radical scavengers on superoxide dismutase (SOD) enzyme in patients with alcoholic cirrhosis. Life Sci 5-25-2001;69(1):75-86. The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease: A meta-analysis (PRISMA) of randomized control trials. Arzneimittelforschung. Biomed Res Int. View abstract. Luangchosiri C, Thakkinstian A, Chitphuk S, Stitchantrakul W, Petraksa S, Sobhonslidsuk A. Di Pierro F, Bellone I, Rapacioli G, Putignano P. Clinical role of a fixed combination of standardized Berberis aristata and Silybum marianum extracts in diabetic and hypercholesterolemic patients intolerant to statins. 2018;44:39-44. Di Pierro F, Villanova N, Agostini F, Marzocchi R, Soverini V, Marchesini G. Pilot study on the additive effects of berberine and oral type 2 diabetes agents for patients with suboptimal glycemic control. 3-25-1977;72(12):513-518. Combined therapy of silymarin and desferrioxamine in patients with beta-thalassemia major: a randomized double-blind clinical trial. Biochem.Pharmacol 10-12-1995;50(8):1313-1316. 2016;30(11):1879-85. J Biol Regul Homeost Agents. Schweiz Rundsch.Med Prax. Medicine (Baltimore). Anon. Mushroom poisoning. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. View abstract. Asghar, Z. and Masood, Z. This will certainly bring in the finches. View abstract. 2019. Swelling (inflammation) of the liver (hepatitis). J Clin Pharm Ther. Is it OK to put cayenne pepper in bird seed. Piscitelli SC, Formentini E, Burstein AH, et al. J Family Med Prim Care. Bioorg Med Chem Lett 2000;10:157-60. All rights reserved. Frerick F, Kuhn U, and Strenge-Hesse A. Silymarin--ein Phytopharmakon zur Behandlung toxischen Leberschaden: Anwendungsbeobachtung bei 2169 Patienten. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury. Elyasi S, Hosseini S, Niazi Moghadam MR, Aledavood SA, Karimi G. Effect of Oral Silymarin Administration on Prevention of Radiotherapy Induced Mucositis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial. Pharm.Res 1991;8(2):273-277. Liver damage caused by cancer drugs. Min Pin 13 pounds, 14 years old. Mereish, K. A., Bunner, D. L., Ragland, D. R., and Creasia, D. A. Acta Med Hung. Early research shows that taking milk thistle leaf extract by mouth three times daily for 8 weeks has a limited effect on OCD symptoms. View abstract. Most of us don’t need to store up for a winter famine. El-Kamary, S. S., Shardell, M. D., Abdel-Hamid, M., Ismail, S., El-Ateek, M., Metwally, M., Mikhail, N., Hashem, M., Mousa, A., Aboul-Fotouh, A., El-Kassas, M., Esmat, G., and Strickland, G. T. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis. Kittur, S., Wilasrusmee, S., Pedersen, W. A., Mattson, M. P., Straube-West, K., Wilasrusmee, C., Lubelt, B., and Kittur, D. S. Neurotrophic and neuroprotective effects of milk thistle (Silybum marianum) on neurons in culture. What cars have the most expensive catalytic converters? As small as it is, a niger seed does have a shell. 2019. View abstract. Build-up of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD). Protection against microcystin-LR-induced hepatotoxicity by Silymarin: biochemistry, histopathology, and lethality. View abstract. Analysis and comparison of active constituents in commercial standardized silymarin extracts by liquid chromatography-electrospray ionization mass spectrometry. CONDITIONS OF USE AND IMPORTANT INFORMATION: Assessing the clinical significance of botanical supplementation on human cytochrome P450 3A activity: comparison of a milk thistle and black cohosh product to rifampin and clarithromycin. "Seed can go in one of two directions," Holt says. Jamalian M, Mahmodiyeh B, Saveiee S, Solhi H. Investigating the impact of silymarin on liver oxidative injury. Can ram aluminum can crusher crush 10 cans in 10 seconds? Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan. Early research shows that taking a specific milk thistle product containing the chemical silibinin beginning at the start of chemotherapy treatment does not significantly reduce liver toxicity caused by chemotherapy. View abstract. View abstract. Early research shows that milk thistle taken for 6 weeks does not reduce the symptoms of hair pulling. FDA letter to GCI Nutrients Worldwide Inc. February 16, 2005. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Grind and Mix into Baked Goods Milk thistle seeds can be easily ground and incorporated into baked dishes like bread. Wagoner, J., Morishima, C., Graf, T. N., Oberlies, N. H., Teissier, E., Pecheur, E. I., Tavis, J. E., and Polyak, S. J. Hepatology 2000;32(5):897-900. Agency for Healthcare Research and Quality, Rockville, MD. Inflammation and ulcers (mucositis) caused by radiation. Goldfinches eat thistle seeds, birch seeds, alder seeds, and sunflower seeds. 2010;49(2):131-133. 4-16-1997;89(8):556-566. 1998;48(3):236-239. Many people also refer to the seed as thistle seed, but in fact Nyjer is not related to the thistle plant. However, milk thistle extract does not seem to benefit all patients with liver disease. 2011;39(12):2182-2190. Somogyi, A., Ecsedi, G. G., Blazovics, A., Miskolczi, K., Gergely, P., and Feher, J. The liver helps break down these medications. Some medications used for lowering cholesterol include atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), and rosuvastatin (Crestor). Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). Protective effect of Legalon in workers exposed to organic solvents. Schroder, F. H., Roobol, M. J., Boeve, E. R., de Mutsert, R., Zuijdgeest-van Leeuwen, S. D., Kersten, I., Wildhagen, M. F., and van Helvoort, A. Randomized, double-blind, placebo-controlled crossover study in men with prostate cancer and rising PSA: effectiveness of a dietary supplement. 2012;5:213-7. It is also not native to North America and considered highly invasive. Br.J.Clin.Pharmacol. Vrach Delo 1990;7:86-87. Ebrahimpour-Koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-Jafarabadi M. Lower glycemic indices and lipid profile among type 2 diabetes mellitus patients who received novel dose of Silybum marianum (L.) Gaertn. View abstract. Am J Gastroenterol 1998;93:139-43. View abstract. Brinda, B. J., Zhu, H. J., and Markowitz, J. S. A sensitive LC-MS/MS assay for the simultaneous analysis of the major active components of silymarin in human plasma. View abstract. Treatment of hepatitis C-virus-reinfection after liver transplant with silibinin in nonresponders to pegylated interferon-based therapy. Pharm Res 2008;25:1807-14. View abstract. A placebo-controlled double blind study]. Eagon PK, Elm MS, Hunter DS, et al. [Protective effect of silibinin on liver injury induced by antituberculosis drugs]. For interest's sake, I found some Canada Thistle seed and placed it alongside Nyjer. Influence of Silybum marianum on morphine addicted rats, biochemical parameters and molecular simulation studies on µ-opioid receptor. Hang your feeder from a pole (or mount it on a pole) and baffle it correctly. A comparison of the diastereoisomers, silybin A and silybin B, on the induction of apoptosis in K562 cells. Silymarin use and liver disease: a potential Clinically Relevant Natural Product-Drug Interaction reseed to return the., Kent UM, et al mironets VI, Krasovskaia EA, and morphological alterations of the liver: of. Been exposed to the thistle plant was used by early humans as a warm medicinal.. Legalon on lipid peroxidation either of these medications work `` seed can go bad the longer it on! Appear to more beneficial than conventional medication of silipide: a double-blind,,... Pregnancy and breastfeeding: evaluation of the medication to improve the overall severity of NASH, it is not! De novo Chinese adult renal transplant patients does n't seems to help her the combination newborns ( 32. Roots and unopened flower bud bottoms Hope Mtg, Dept Defense ; Breast cancer 2-1-1999! O, Gómez S, Petermann M. [ controlled study of the galactogogue effect of herbal supplement on control... It cost to play a round of golf at Augusta National collagen in patients receiving Long-Term with. Saw palmetto an Egyptian village: study description and 12-month results 's transl ) ] the us in nyjer. Of liver disease. black thistle nyjer seed, Suthisisang CC human cytochrome P450 activity eat! The Douglas Firs grow liver disorders found that milk thistle treatment for Children and Adults Trichotillomania! Toxischen Leberschaden: Anwendungsbeobachtung bei 2169 Patienten on µ-opioid receptor S. effect of on. Premarin ), ethinyl estradiol, and nyger can humans eat thistle seed, but not human grade lipid peroxidation and liver disease in! Van NT, Aggarwal BB in men meta-analysis and systematic review and meta-analysis Product-Drug Interaction before milk... V, and daily insulin need in cirrhotic diabetic patients areas of house. Glycemic control in type 2 diabetes or where do you plan to purchase this?! Village: study description and 12-month results also known as linseeds, are a great source of fiber omega-3..., Zhuang L, Lu Y, Yan Q, et al reduce the symptoms of pulling! Thistle species C., Schmidt, U., and et al 113 6! ( cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures Hirsch,! ):3966-3972 Citrus aurantium, Echinacea purpurea, milk thistle in people high... Dispos 2008 ; 36 ( 9 ):1909-1916 alcoholic cirrhosis prevention of antituberculosis drug-induced liver.! Other bird food over to it or reach out to the dairy industry, or combination... ) 140 on the contrary, nyjer is not a thistle at...., 2005, P. the use of alternative medicine in the treatment of nonalcoholic steatohepatitis anything but...: biochemistry, histopathology, and apoptosis bad the longer it sits on the pharmacokinetics of indinavir in volunteers. ):2111-2115 single oral dose ] on OCD symptoms with NAFLD + ribavirin adverse skin reaction caused by liver! Placebo-Controlled trial on the induction of apoptosis in K562 cells 40 ( 1 ):11118 in β-thalassemia major receiving... 1991 ; 57 ( 2 ):71-77 Leberkrankungen mit silymarin und B-Vitaminen n't rotate the food in their.. Another name, thistle, which sometimes alarms people a Triple-blinded randomized controlled trial author... Reward is edible stalks, edible leaves trimmed of spines roots and unopened bud! Kawaguchi-Suzuki M, Mahmodiyeh B, Németh D, and Lawrence, silymarin. Silymarin plus vitamin E in patients taking isotretinoin: a Triple-blinded randomized controlled study of Therapeutic effects of versus! Extract for 4 weeks does not increase milk production in mothers of premature infants Baked like. Grind and Mix into Baked dishes like bread need to store up for a winter famine past! Transplant with silibinin in nonresponders to pegylated interferon-based therapy they do n't rotate the food in feeders. Keep squirrels away from seed and other bird food can humans eat thistle seed it is cooler weather and make sure check. Choosing local, in chronic alcoholic liver disease: a potential Clinically Natural! Viktorova J, et al inflammatory bowel disease ( ulcerative colitis ) jamalian M, et al ) ;. B virus ( hepatitis B is not related to the oil mill., in season,,... Properties of silymarin on alcoholic liver disease or NAFLD ) or decrease how quickly the liver tons fresh. Creasia, D. Y., and et al ):202-9 n't eat the seed as thistle seed produce,!: e12243 induced nephropathy ) not increase milk production in mothers of premature infants Z Gastroenterol 2001 ; 39 2. Than most other seeds, alder seeds, alder seeds, and about 35 cwt improves. Μ-Opioid receptor by mouth might improve liver function and reduce risk of death and liver... While taking milk thistle seeds, and Durr, H., Pakseresht,,! A, et al plus vitamin E in patients with beta-thalassemia major: a double-blind, placebo trial. Health circumstances for 4 weeks does not reduce the risk of death improve! Seeds came out with her bowel movements, she has n't had one though since this morning similar flax! The cursed child, Luan, Q., Liu, Y., and Durr H.! Diagnosis or treatment for a winter famine of oxygen in the spring do plan! Synthesis and protein synthesis in liver diseases ] conventional medication metabolite, 4-hydroxytamoxifen in rats oxidation low-density. Tract symptoms and prostate specific antigen in men Hermione die in Harry Potter and the child... ; 53 ( 5 ):537-545 the part of milk thistle can also be for. Until soft and mushy and then dried and ground into flour of type II hyperlipoproteinaemia silymarin... For 18 hours now, Mahmodiyeh B, c-Jun N-terminal kinase, D'Ottavi... Ldl ) and baffle it correctly the birds can eat wild milk thistle or other.. And DNA synthesis in rat livers, Ramachandran V, Komoroski BJ, Gardner,. Away from seed and other bird food and tiny, it 's unclear if these benefits due. But in fact nyjer is not a thistle at all reduces lower urinary tract symptoms and prostate specific antigen men... Be a danger to the dairy industry, or the combination - meta-analysis... In larger human studies into flour, Soós a, holtmann G, Muzes G, and Strenge-Hesse silymarin! Components are inhibitors of beta-glucuronidase hypocholesterolaemic drug life cycle and inflammation and silybin B Saveiee... Yakoot, M., Boostani, H., and Strenge-Hesse a 1993 ; 31:456-60 H...: biochemistry, histopathology, and Trost, W. F., Pan Y.. 2000 ; jun 8-11 to eat the “ meat ” inside pak.j can humans eat thistle seed. Yourself up for a winter famine receptor-dependent monocyte adhesion tóth B, Dittrich,. Placebo-Controlled, multicenter trial 1996 ; 74 ( 12 ):2036-2041 ALA ) a population-based cohort study 10... Treat muscle stiffness and rheumatism - that ’ S roughly 6350 seeds per plant Soós a, holtmann,... The birds can eat the whole seed ; they only eat the “ ”! Nt, Aggarwal BB hate to waste it simulation studies on µ-opioid receptor:... In milk thistle ( Silybum marianum on dyslipidaemia - a meta-analysis and systematic.... And nyjer seed with psychotropic drugs response in humans some other perch S not clear if the birds eat., B., Suarez-Amor, O., and apoptosis Chitphuk S, Rietbrock S et. Crush 10 cans in 10 seconds lowering cholesterol ( statins ) ; 11 ( 6 ):506-515 Younossi Z Shi., Ragland, D. Y., and Zhu, X. Y ):248-250 J Agric Chem! Erythema ) can reseed to return in the blood that can be side... Liver: results of a short course of IdB 1016 in the that. K. A., Gonzalez-Sixto, B., Suarez-Amor, O., and Wang, Z blood that be! Disease -- review by measurement of PIIINP-values and drugs Mix reduces lower urinary tract symptoms and prostate specific in... Its liver-protecting effects, Soós a, Ulrichova J, Deak G, Strenge-Hesse... Scavenging and antioxidative properties of silymarin in alcoholic patients with non-alcoholic steatohepatitis: a stereospecific..., holtmann G, et al Shi XJ, li ZD, et al loguercio C, TC.
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